Variation in CYP2A6 Activity and Personalized Medicine
نویسندگان
چکیده
منابع مشابه
Variation in CYP2A6 Activity and Personalized Medicine
The cytochrome P450 2A6 (CYP2A6) enzyme metabolizes several clinically relevant substrates, including nicotine-the primary psychoactive component in cigarette smoke. The gene that encodes the CYP2A6 enzyme is highly polymorphic, resulting in extensive interindividual variation in CYP2A6 enzyme activity and the rate of metabolism of nicotine and other CYP2A6 substrates including cotinine, tegafu...
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ژورنال
عنوان ژورنال: Journal of Personalized Medicine
سال: 2017
ISSN: 2075-4426
DOI: 10.3390/jpm7040018